牙膏中6﹘甲基香豆素、二氢香豆素、 7﹘甲基香豆素、7﹘甲氧基香豆素、 7﹘乙氧基﹘4﹘甲基香豆素的测定 高效液相色谱法 Determination of 6﹘methylcoumarin, dihydrocoumarin, 7﹘methylcoumarin, 7﹘methoxycoumarin, 7﹘ethoxy﹘4﹘methylcoumarin in toothpastes— High performance liquid chromatography  ICS  71.100.40 CCS  Y 43   中华人民共和国国家标准 GB/T 44365—2024 2024-08-2 3发布 2025-03-0 1实施     国家市场监督管理总局 国家标准化管理委员会 发 布 目　　次 前言   ·····································································································   Ⅲ 1     范围   ··································································································   1 2     规范性引用文件   ······················································································   1 3     术语和定义   ···························································································   1 4     原理   ··································································································   1 5     试剂和材料   ···························································································   1 6     仪器设备   ······························································································   2 7     试验步骤   ······························································································   2      7.1     试样溶液的制备   ·················································································   2      7.2     测定   ······························································································   2      7.3     标准工作曲线   ····················································································   3      7.4     试样测定   ·························································································   3      7.5     空白试验   ·························································································   3 8     结果计算   ······························································································   3 9     回收率   ································································································   4 10     精密度   ·······························································································   4 11     检测限和定量限   ·····················································································   4 附录 A （资料性）　标准物质/标准样品信息   ···························································   5 附录 B （资料性）　5种香豆素标准溶液的色谱图和光谱图   ············································   6 附录 C （资料性）　确证试验   ··········································································   10 　C.1　液相色谱参考工作条件   ·········································································   10 　C.2　质谱参考工作条件   ··············································································   10 　C.3　定性测试   ························································································   11 GB/T 44365—2024     Ⅰ